Definition
Introduced in 2020 (Eklund et al., 2020), the component Sample is a portion or quantity of biological material that is collected from a sample donor, or a digital representation of a biological entity of the sample donor, such as an image.
| Attribute Code | Attribute Name | Description | Data type | Allowed values | Constraints | Cardinality |
|---|---|---|---|---|---|---|
| MIABIS-SAMPLE-01 | Sample ID | Unique ID of the sample within a sample collection, often represented by the sample barcode; text identifier. The Sample ID is meant for sharing. | String | Pseudonymized, alphanumeric. It is recommended that sample IDs are persistent within a given biobank. | 1 | |
| MIABIS-SAMPLE-02 | Sample type | The type of biological specimen intended for testing diagnostics, disease propagation, treatment, or for research purposes. | Enumerated values | Amniotic fluid; Ascites fluid; Bile; Body cavity fluid; Bone; Bone marrow aspirate; Bone marrow plasma; Bone marrow, whole; Breast milk; Bronchoalveolar lavage; Buffy Coat; Cancer cell lines; Cerebrospinal fluid; Cord blood; Dental pulp; DNA; Embryo; Entire body organ; Faeces; Fetal tissue; Fibroblasts; Food specimen; Gas, exhaled (=breath); Gastric fluid; Hair; Immortalized cell lines; Isolated microbes; Isolated or enriched exosomes; Isolated Tumor Cell (neoplastic cell); Menstrual blood; Nail; Nasal washing; Organoids; Pericardial fluid; Peripheral blood mononuclear cells (PBMC); Placenta; Plasma; Pleural fluid; Post-mortem tissue; Primary cells; Protein; Red blood cells; RNA; Saliva; Semen; Serum; Specimen from environment; Sputum; Stem cells (and iPS cells); Swab; Sweat; Synovial fluid; Tears; Teeth; Tissue (fixed); Tissue (fresh frozen); Umbilical cord; Urine; Urine sediment; Vitreous fluid; Whole blood; Whole blood, dried (e.g. Guthrie cards); Other | 1 | |
| MIABIS-SAMPLE-03 | Sample storage temperature | The long-term temperature at which the sample is stored after preparation, based on SPREC v4 and MIABIS-COLLECTION-15. | Enumerated values | RT (Room temperature), 2 °C to 10°C, -18 °C to -35 °C, -60 °C to -85 °C, <-135 °C, Liquid nitrogen vapor-phase, Liquid nitrogen liquid-phase, Other. | 0..1 | |
| MIABIS-SAMPLE-04 | Sample creation date and time | The date and time the sample was created in the form previously described in MIABIS-SAMPLE-02. | Datetime, yyyy-mm-ddThh:mm:ss | Datetime format must be according to ISO 8601. However, partial values, eg. YYYYY, are allowed if more detailed date information is not available. | 0..1 | |
| MIABIS-SAMPLE-05 | Anatomical site | The anatomical source of the sample material. | Structured attribute | 0..1 | ||
| MIABIS-SAMPLE-05-01 | Anatomical site ontology | Name of ontology used for describing the anatomical source of the sample material, for example, ICD-O-3 topography code. | String | MIABIS-SAMPLE-05-01 and MIABIS-SAMPLE-05-02 are required if any anatomical site information is provided. | 0..1 | |
| MIABIS-SAMPLE-05-02 | Anatomical site ontology version | Version of selected ontology for anatomical site. | String | MIABIS-SAMPLE-05-01 and MIABIS-SAMPLE-05-02 are required if any anatomical site information is provided. | 0..1 | |
| MIABIS-SAMPLE-05-03 | Anatomical site ontology code | Anatomical site code from the selected anatomical site ontology version. | String | 0..1 | ||
| MIABIS-SAMPLE-05-04 | Anatomical site ontology description | Description from the selected anatomical site ontology code. | String | 0..1 | ||
| MIABIS-SAMPLE-05-05 | Anatomical site free text | Explanation about Anatomical site in case of unknown Anatomical site or insufficient information. | String | 0..1 | ||
| MIABIS-SAMPLE-10 | Sample content diagnosis | The ICD-10 or ORPHA code describing the diagnosis of the sample content, such as whether the sample contains carcinogenic material. | Enumerated values | Use the value code from ICD-10 or ORPHA classifications. | 0...n | |
| MIABIS-SAMPLE-11 | Use & Access conditions | The conditions that may change the availability of the samples donated by the sample donor. | Enumerated values | Commercial use, Collaboration, Specific research use, Genetic data use, Outside EU access, Xenograft, Other animal work, Other. | 0...n | |
| MIABIS-SAMPLE-12 | Sample source | The source from which the samples were collected or isolated. | Enumerated values | Human, Animal, Environment. | 0..1 |